I hate Rain-X 2-in-1 Glass Cleaner. It smeared and reduced visibility significantly at night. Some people say it's the fabric softener in the paper towel, some say it's the wipers, and some say they have the method for getting Rain-X to work. But I hate it. It also doesn't repel rain very well. I was the only one on the road with beads on rain on the window, when everyone else had perfectly clear windows. Stay away from Rain-X 2-in-1 Glass Cleaner!
Apparently Rain-X forms some sort of silicon film over the window, so you can't clean it off easily. I've had to abrade it off with Bon Ami Cleaning Powder and then clean the windshield with lighter fluid and then with Invisible Glass (apply with newspaper, then wipe clean with microfiber cloth). What a pain in the neck!!!
The directions on the Rain-X bottle were misleading. They should have come with some sort of warning and detailed instructions on avoiding problems.